Marcella Rydmark

Marcella Rydmark

Project manager

Affiliation Natural History Museum, University of Oslo

Email

About

I am a structural biologist with an interest in membrane proteins and lipids and how they interact. Approximately 70% of all pharmacological drugs act upon membrane proteins, making them a uniquely important target for drug discovery purposes. 

During my PhD at the University of Oxford, UK (2008-2012), I studied a sub-group of membrane proteins called G-protein coupled receptors, and how they undergo conformational changes in a membrane environment, using a variety of spectroscopic tools. I also did a considerable amount of with work with a biotech form, Malvern Cosmeceutics, using polymers for the direct extraction of membrane proteins into nanosized-lipid discs. During my Postdoc at the FMP in Berlin, I dove deeper into spectroscopy, working on a technique called 'Dynamic Nuclear Polarization', which has the potential to revolutionize diagnostic tools such as MRIs, by providing a 100-fold increase in sensitivity in comparison to today's most modern methods. During this period, I also had the privilege to mentor a number of students, something I enjoyed immensely.  

During my second Postdoc at UiO, I was able to combine my passion for both spectroscopy and membrane proteins, working on a project where we are trying to solve the structure of a membrane protein within a real cellular membrane at atomic resolution. If this project proves to be successful, which we are very hopeful of, it will be a world-first, and constitute a major breakthrough in how we are able to study the structures of these incredibly important drug targets.  

Currently, I am the Project Manager for Plant.ID and am based at the Natural History Museum in Oslo. I support the students, professors, and project in all aspects of organization and administration, so that they can focus on performing world-class research. As a lifelong learner and lover of science, I am also looking forward to learning a huge amount of new and interesting information on plants and how to identify them at the genetic and molecular level!